How am I supposed to know when to or what vaccines to give my APBT, which one for monthly and which for annually? I currently give Duramune Max 5 CVK/4L once a month it's an 8 way shot.

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as a responsible dog owner, you need to find a trustworthy veterinarian. take your dogs to the vet regularly and follow their advice. a good vet will know everything about all the medications your dog may need.